Randomised controlled trial of homoeopathy versus placebo in perennial allergic rhinitis with overview of four trial series

OBJECTIVE: To test the hypothesis that homoeopathy is a placebo by examining its effect in patients with allergic rhinitis and so contest the evidence from three previous trials in this series. Design: Randomised, double blind, placebo controlled, parallel group, multicentre study. SETTING: Four general practices and a hospital ear, nose, and throat outpatient department. PARTICIPANTS: 51 patients with perennial allergic rhinitis. Intervention: Random assignment to an oral 30c homoeopathic preparation of principal inhalant allergen or to placebo. MAIN OUTCOME MEASURES: Changes from baseline in nasal inspiratory peak flow and symptom visual analogue scale score over third and fourth weeks after randomisation. RESULTS: Fifty patients completed the study. The homoeopathy group had a significant objective improvement in nasal airflow compared with the placebo group (mean difference 19.8 l/min, 95% confidence interval 10.4 to 29.1, P=0.0001). Both groups reported improvement in symptoms, with patients taking homoeopathy reporting more improvement in all but one of the centres, which had more patients with aggravations. On average no significant difference between the groups was seen on visual analogue scale scores. Initial aggravations of rhinitis symptoms were more common with homoeopathy than placebo (7 (30%) v 2 (7%), P=0.04). Addition of these results to those of three previous trials (n=253) showed a mean symptom reduction on visual analogue scores of 28% (10.9 mm) for homoeopathy compared with 3% (1.1 mm) for placebo (95% confidence interval 4.2 to 15.4, P=0.0007). CONCLUSION: The objective results reinforce earlier evidence that homoeopathic dilutions differ from placebo

Previous injury as a risk factor for re-injury in rock climbing: A secondary analysis of data from a retrospective cross sectional cohort survey of active rock climbers

Background The aim of this article is to report the findings of a secondary analysis of a previous injury study to consider previous injury as a risk factor for reinjury in rock climbing. Methods We completed a secondary analysis of 201 questionnaires that were gathered as part of a retrospective cross-sectional cohort survey that investigated the epidemiology of injuries in a representative sample of British rock climbers. Participants had actively engaged in rock climbing over the previous 12-month period and were recruited from six indoor climbing centres and five outdoor climbing venues (men n=163, mean±SD, age=35.2±11.8 years, participating in rock climbing=13.88+11.77 years; women n=38, mean±SD, age=35.1±10.7 years, participating in rock climbing=11.62+9.19 years). Results Of the 101 participants who sustained a previous injury, 36 were found to have sustained at least one reinjury. The total number of reinjuries was 82, with the average probability of sustaining at least one reinjury being 35.6% (95% CI 34.71% to 36.8%; p<0.001, McNemar's χ2 test) with the relative risk of reinjury being 1.55 (95% CI 1.34 to 1.80). The fingers were the most common site of reinjury (12 participants, 26%; χ2=43.12, df=5, p<0.001). Conclusions Previous injury was found to be a significant risk factor for reinjury, particularly at the site of the fingers. Technical difficulty in bouldering and sport climbing behaviours were significantly associated with repetitive overuse reinjury. As participatory figures increase, so does the likelihood that a high proportion of climbers may sustain a reinjury of the upper extremity

VICTour 1.1: Introducing virtual learning environments and gamification

Game engines are one of the few solutions to providing a true virtual campus tour experience. In this paper, we explore the evolution of the virtual campus tour and thereby the current and future work of game technology within virtual touring. An investigation is conducted into the application of objective-based gamification and its ability to encourage exploration of a virtual world. We also examine virtual campus tours as an alternate form of taught content via virtual learning environments (VLEs). An investigation into the use of head mounted displays to improve immersion is also explored

A User-Centred Approach to Reducing Sedentary Behaviour

The use of digital technologies in the administration of healthcare is growing at a rapid rate. However, such platforms are often expensive. As people are living longer, the strain placed on hospitals is increasing. It is evident that a usercentric approach is needed, which aims to prevent illness before a hospital visit is required. As such, with the levels of obesity rising, preventing this illness before such resources are required has the potential to save an enormous amount of time and money, whilst promoting a healthier lifestyle. New and novel approaches are needed, which are inexpensive and pervasive in nature. One such approach is to use human digital memories. This outlet provides visual lifelogs, composed of a variety of data, which can be used to identify periods of inactivity. This paper explores how the DigMem system is used to successfully recognise activity and create temporal memory boxes of human experiences, which can be used to monitor sedentary behaviour

Capturing and Sharing Human Digital Memories with the Aid of Ubiquitous Peer– to–Peer Mobile Services

The explosion of mobile computing and the sharing of content ubiquitously has enabled users to create and share memories instantly. Access to different data sources, such as location, movement, and physiology, has helped to create a data rich society where new and enhanced memories will form part of everyday life. Peer–to–Peer (P2P) systems have also increased in popularity over the years, due to their ad hoc and decentralized nature. Mobile devices are “smarter” and are increasingly becoming part of P2P systems; opening up a whole new dimension for capturing, sharing and interacting with enhanced human digital memories. This will require original and novel platforms that automatically compose data sources from ubiquitous ad-hoc services that are prevalent within the environments we occupy. This is important for a number of reasons. Firstly, it will allow digital memories to be created that include richer information, such as how you felt when the memory was created and how you made others feel. Secondly, it provides a set of core services that can more easily manage and incorporate new sources as and when you are available. In this way memories created in the same location, and time are not necessarily similar – it depends on the data sources that are accessible. This paper presents DigMem, the initial prototype that is being developed to utilize distributed mobile services. DigMem captures and shares human digital memories, in a ubiquitous P2P environment. We present a case study to validate the implementation and evaluate the applicability of the approach

Red Button and Yellow Button: Usable Security for Lost Security Tokens

Currently, losing a security token places the user in a dilemma: reporting the loss as soon as it is discovered involves a significant burden which is usually overkill in the common case that the token is later found behind a sofa. Not reporting the loss, on the other hand, puts the security of the protected account at risk and potentially leaves the user liable. We propose a simple architectural solution with wide applicability that allows the user to reap the security benefit of reporting the loss early, but without paying the corresponding usability penalty if the event was later discovered to be a false alarm.The authors with a Cambridge affiliation are grateful to the European Research Council for funding this research through grant StG 307224 (Pico). Goldberg thanks NSERC for grant RGPIN-341529. We also thank the workshop attendees for comments

Plasma Physics

Contains research objectives and reports on three research projects.United States Atomic Energy Commission (Contract AT(30-1)-1842

A User-Centred Approach to Reducing Sedentary Behaviour

The use of digital technologies in the administration of healthcare is growing at a rapid rate. However, such platforms are often expensive. As people are living longer, the strain placed on hospitals is increasing. It is evident that a usercentric approach is needed, which aims to prevent illness before a hospital visit is required. As such, with the levels of obesity rising, preventing this illness before such resources are required has the potential to save an enormous amount of time and money, whilst promoting a healthier lifestyle. New and novel approaches are needed, which are inexpensive and pervasive in nature. One such approach is to use human digital memories. This outlet provides visual lifelogs, composed of a variety of data, which can be used to identify periods of inactivity. This paper explores how the DigMem system is used to successfully recognise activity and create temporal memory boxes of human experiences, which can be used to monitor sedentary behaviour

Remotely Monitoring and Preventing the Development of Pressure Ulcers with the Aid of Human Digital Memories

There is growing concern, among senior personnel in the National Health Service in the UK, over the increased development of pressure ulcers. The occurrence of pressure ulcers has been attributed to prolong sedentary behaviour. Providing care, for this preventable condition, is costly and time-consuming for patients and medical practitioners. Extra bedside assistance is needed; however, with the workload of medical staff increasing, this is not always practical. In order to prevent the occurrence of pressure ulcers new and novel ways of remotely monitoring patients is essential. An interesting approach worth considering is the use of human digital memories, which provide visual life logs of a patient’s physiological and environmental data. This paper discusses some of the current technologies used within the area and how they might be applied to the management and prevention of pressure ulcers. We have successfully developed a working prototype system to demonstrate the applicability of our approach

A User-Centred Approach to Reducing Sedentary Behaviour

The use of digital technologies in the administration of healthcare is growing at a rapid rate. However, such platforms are often expensive. As people are living longer, the strain placed on hospitals is increasing. It is evident that a usercentric approach is needed, which aims to prevent illness before a hospital visit is required. As such, with the levels of obesity rising, preventing this illness before such resources are required has the potential to save an enormous amount of time and money, whilst promoting a healthier lifestyle. New and novel approaches are needed, which are inexpensive and pervasive in nature. One such approach is to use human digital memories. This outlet provides visual lifelogs, composed of a variety of data, which can be used to identify periods of inactivity. This paper explores how the DigMem system is used to successfully recognise activity and create temporal memory boxes of human experiences, which can be used to monitor sedentary behaviour